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Quick Facts Product: Enabling vaccines to be delivered and transported without refrigeration Patents: [this section redacted] Customers: Global health groups including World Health Organization; medical and vaccine suppliers Financing Sought: $1.5 million Use of funds: Lab equipment; materials; lab rental; marketing; manufacturing; hiring additional research scientists; legal Contact: Ting-Ting Zhou,  ting-ting@nanoly.info

Summary According to the World Health Organization (WHO), 26 million children are not immunized, exposing them to disabilities or premature death. Globally, 2.1 million people die each year from vaccine-preventable diseases. In 2008 alone, 1.7 million deaths for children under the age of 5 were attributed to vaccine preventable diseases. People living in hard-to-reach areas of the world struggle to receive immunization. Nanoly’s technology enables the cheap, effective, and safe delivery of vaccines to anywhere in the world.  [this section redacted]

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Vaccines are heat-sensitive and must be kept refrigerated. The vaccine “cold chain” is the system of transporting and storing vaccines within the temperature range of 35°F (2°C) to 45°F (8°C).  If exposed to temperatures too high or too low, the vaccine will spoil or denature and become inactive. Injecting a spoiled vaccine reduces the potency and leaves the patient susceptible to the vaccine-preventable disease. This strict vaccine refrigeration requirement contributes to the 25% liquid vaccine wastage rate estimated by the WHO.  The wastage rate for 10-20 vaccine dose vials is even higher, at an astounding 50%. The process also hinders the delivery of vaccines to remote areas of the world where there is no electricity to operate refrigerators. Of the 26 million children in the world who are not vaccinated in the world, 68% live in countries with the weakest immunization structures caused by transportation difficulties. 

The World Health Organization summarizes the current vaccine supply chain in low to middle-income countries into 12 steps.

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UNICEF, the World Health Organization, and countries with the lowest immunization rates all state improved immunization methods as a goal.  UNICEF stated that the vaccine “Cold Chain and Logistics systems are aging and often insufficient to accommodate the new vaccines.” The United Nations’ Millennium Development Goal #4 is to reduce the under-five child mortality rate by two-thirds from 1990 to 2015.  In order to achieve this, the WHO and UNICEF established the “Global Immunization Vision and Strategy 2006-2015.” In WHO and UNICEF’s document, the organizations list 1) immunizing "hard to reach" infants and 2) increase the availability and affordability of new life-saving vaccines as top priorities.  NanoShield by Nanoly is the ideal replacement for the costly refrigerated cold chain.